Another favourite of ours from last year was Siena.  Siena is famous for a lot of things.  The two main ones that impressed us the most are the Piazza del Campo, and the Siena Cathedral.  One famous for its annual horse race, and the other for it beautiful black and white marble architecture.  There is also a great coffee shop that we visited last year and found it again this year.  Great shopping and more fine churches and museums and piazzas than you could visit in a day.  We spent an entire afternoon here and went home exhausted.